The Role of Cytology in the Diagnosis of Metastatic Hepatocellular Carcinoma

The diagnosis of primary hepatocellular carcinoma (HCC) in high risk patients, such as those with chronic hepatitis B or C with/without cirrhosis the liver, can be made relevant image studies alone; however, morphologic confirmation by cytology histopathology is essential to metastatic HCC because treatment latter differs from that extrahepatic malignancy. Although both and are important tools malignancy, almost always plays a confirmatory pivotal role, also gold standard cyto-histological correlation. We present two patients rare sites; endobronchus one, neck lymph nodes, face abdominal wall other. Repeated bronchial biopsy first patient excisional sites second failed make conclusive HCC. However, brushing fine needle aspiration respective consistently showed characteristic features provided clinicians rationale for ongoing treatment. diagnostic issues possible pitfalls discussed. Cytology appear equipollent; sometimes play role when fails its expected this scenario.